Perioral dermatitis is an inflammatory reaction in the skin that causes red bumps and rash around the mouth, nose, and in some cases the eyes. The condition is often mistaken for acne or rosacea — but differs by a characteristic clear band of unaffected skin right up to the lips. It most commonly affects women from age 20 and up, and is not necessarily chronic with proper care.
What is perioral dermatitis?
Perioral dermatitis is a skin condition that causes irritated skin and redness around the mouth, nose, and — in some cases — the eyebrows and forehead. In short, it is caused by an imbalance in the skin. The condition alters the skin’s structure and is often associated with social insecurity and can generally create an uncomfortable sensation in the face. Perioral dermatitis most often affects women from their 20s and onwards.
Redness can appear as small red sebaceous bumps — both with and without inflammation — and will likely spread over time if the inflammation is not controlled.
Typical causes of perioral dermatitis
The causes of perioral dermatitis can be many, and for most people it is not a single factor that triggers the condition. Research points to a combination of microbiome imbalance, irritants, and hormonal factors. The most common causes are:
- Hair follicle mites (Demodex mites) — microscopic mites living in sebaceous glands and hair follicles. When they multiply uncontrollably, they can trigger inflammatory reactions resembling perioral dermatitis
- Strong steroid creams — one of the most common triggering causes, especially with prolonged use of corticosteroids on the face
- Overly rich moisturizers — occlusive care that "seals" the skin can disrupt the skin’s natural balance and create favorable conditions for bacteria and mites to thrive
- Neglected facial cleansing — buildup of sebum, dirt, and bacteria worsens inflammation over time
- Fluoride in toothpaste — fluoride is a documented trigger, especially when located periorally around the mouth
- Inhaled steroids — asthma medication via inhaler can in some cases contribute to the condition
- Extreme weather conditions — wind, cold, and intense heat can further worsen the condition
What to avoid with perioral dermatitis
With perioral dermatitis, what you stop doing is just as important as what you start. Here are the four most common mistakes — and they can keep the condition going even when you do everything else right:
1. Steroid creams — even mild ones
It may seem obvious to use a corticosteroid cream to quickly reduce redness. But steroids are actually one of the primary causes of perioral dermatitis. Although they provide short-term relief, the skin typically flares up even more severely once you stop. The result can be a "steroid-dependent" skin that is much harder to treat than the original condition. Avoid steroid creams on the face entirely unless a dermatologist specifically prescribes them for another purpose.
2. Heavy, rich creams and oils
Heavy creams with occlusive effects can block pores and create ideal growth conditions for bacteria and Demodex mites. Instead of more moisture, switch to a light, non-comedogenic cream that does not unnecessarily burden the skin.
3. Acid-based actives — AHA, BHA, and retinol
Exfoliating acids like glycolic acid (AHA) and salicylic acid (BHA) are popular in many skincare products, but with active perioral dermatitis, they are too aggressive. They can further break down the skin barrier and worsen inflammation. The same applies to retinol in most cases. Pause active ingredients until the skin has calmed down.
4. Strong toothpaste with fluoride and whitening effect
Fluoride is a documented trigger, especially for rashes located close to the mouth. Try switching to a mild, fluoride-free toothpaste during flare-ups — and rinse thoroughly around the mouth after brushing.
Redness Relieving Cream — works where other creams fail
Zinc oxide and sulfur reduce active inflammation and redness in perioral dermatitis. Natural ingredients in a mild, gentle formula.
Try Redness Relieving Cream →Treatment of perioral dermatitis
At NIMO SKIN, we are committed to helping you overcome perioral dermatitis. Fortunately, this skin condition is not necessarily chronic, and with the right products, it can be managed to the extent that it no longer bothers you. Even if the skin’s condition seems overwhelming, we just need to remember that good results can be achieved surprisingly quickly — and it all starts with a good and gentle skincare routine.
The products on this page have helped many people with this exact skin condition. With a combination of healthy products and good facial hygiene, you will very likely be able to enjoy life with healthy skin before you know it.
With our face packages, you get everything the skin needs to overcome the challenges that perioral dermatitis brings:
-
DemSol Mild Foam Cleanser is developed for troublesome skin conditions such as perioral dermatitis, rosacea, and acne. It is produced with the aim of gently cleansing the face before applying ZZ-Cream, but can also be used with any other day or night cream.
The ingredients are carefully selected to be gentle on the skin, and regarding the soap, it can be added that it:
- Does not contain perfume
- Removes makeup
- Does not dry out the skin
- Does not sting the eyes
- ZZ-Cream is our little miracle worker. In our opinion, this product is the ultimate solution for those struggling with rosacea, acne, or perioral dermatitis! The unique formula, with ingredients such as zinc oxide, sulfur, glycerin, and Chinese herbs, helps reduce redness, irritation, and inflammation while keeping your skin hydrated and protected.
-
Finally, our face packages include a moisturizer based on your skin type. If you have normal to oily skin, you should choose the package that includes the DemSol Moisturizer. This product absorbs quickly into the skin without leaving it greasy. Some of the wonderful properties of this product include:
- Moisturizing and hydrating
- Reduces itching and redness
- Helps reduce acne scars
- Helps lighten dark spots from acne-damaged skin
- If you have normal to dry skin, it is recommended that you choose the package that includes the Grums Hydra Calm Cream. This cream is made with concentrated hydrating ingredients, along with extract from recycled coffee grounds, which helps with protective antioxidants, caffeine, and vitamin B3. The cream is perfect for both dry and sensitive skin, as it helps increase the skin’s moisture level and supports the skin barrier.
When should you see a doctor for perioral dermatitis?
Most people with perioral dermatitis can manage well with a consistent and gentle home care routine. But there are situations where it is wise to seek professional help:
- The condition spreads quickly to cheeks, eyes, or forehead in a short time
- You have used steroid cream on your face for more than 2-3 weeks — tapering should be gradual, as the skin can otherwise flare up strongly
- Pustules with pus appear or visible signs of secondary bacterial infection
- The condition worsens despite correct care after 4-6 weeks of a mild, consistent routine
- You are pregnant, breastfeeding, or planning pregnancy — certain treatments require special consideration
A dermatologist can assess whether a short course of topical metronidazole — a gel that directly reduces inflammation — or oral antibiotics like doxycycline are needed. These treatments are effective but work best in combination with a gentle daily care routine that does not further irritate the skin.
Frequently asked questions about perioral dermatitis
Can perioral dermatitis go away on its own?
In mild cases, perioral dermatitis can subside over time — especially if you remove the triggering cause, such as a steroid cream or a heavy moisturizer. But for most, it requires an active and consistent care routine for the condition to calm down. Without treatment, you risk the redness and bumps spreading further.
Is perioral dermatitis contagious?
No, perioral dermatitis is not contagious and cannot be transmitted from person to person. The condition arises internally — as a reaction to triggers in your skin, your skincare products, or your hormonal balance. You can safely be around others without risk of infection.
What is the difference between perioral dermatitis and rosacea?
Both conditions cause redness and bumps on the face, but there are important differences. Rosacea most often affects the cheeks and nose and is often associated with flushing — redness that comes and goes. Perioral dermatitis is more localized around the mouth and nose, and the skin right next to the lips is typically free of rash. If you are unsure about your diagnosis, it is a good idea to consult a dermatologist.
Can I wear makeup if I have perioral dermatitis?
It is recommended to minimize makeup in the affected area during an active flare-up — especially heavy foundations and concealers that can clog pores and worsen inflammation. Choose mineral-based makeup without perfume and silicone if possible. And always cleanse thoroughly and gently in the evening — it is one of the most important things you can do for your skin.
What are the best ingredients for perioral dermatitis?
Zinc oxide and sulfur are two of the best-documented substances against active inflammation in perioral dermatitis. Zinc works antibacterial and anti-inflammatory, while sulfur helps regulate sebum production and combat Demodex mites. Avoid perfume, alcohol, acid activators (AHA/BHA), and steroids during the active phase.
What triggers a flare-up of perioral dermatitis?
The most common triggers are steroid creams, heavy moisturizers, fluoride in toothpaste, stress, hormonal fluctuations — e.g., related to menstruation — UV radiation, and heat. A skin diary can help you identify your personal patterns: note what you have used, eaten, and experienced in the days leading up to a flare-up.
How long does it take to get rid of perioral dermatitis?
It varies from person to person. With a consistent and gentle routine, many see a clear improvement within 4-8 weeks. If the condition has been present for a long time or triggered by steroid use, it may take a bit longer — but stick to the routine. Good results can be achieved surprisingly quickly once the skin finally gets the right conditions.
Ready to calm your skin?
Redness Relieving Cream with zinc oxide and sulfur is designed for sensitive skin with active inflammation. Simple, proven, and gentle.
See Redness Relieving Cream here →References
- Habeshian KA, Cohen BA — Perioral Dermatitis (2020). StatPearls Publishing / NCBI Bookshelf.
- Sundhed.dk — Perioral Dermatitis — The Danish Health Authority’s Medical Handbook. Sundhedsstyrelsen.
- Nguyen V, Eichenfield LF — Perioral Dermatitis (2018). StatPearls. PubMed PMID: 30247843.
- Tüzün Y et al. — Sulfur and Its Derivatives in Dermatology: Insights Into Therapeutic Applications (2025). PMC / National Library of Medicine.
- Gupta M et al. — Effects of Zinc Supplementation on Inflammatory Skin Diseases: A Systematic Review (2020). PubMed PMID: 31745908.
0 comments